The first-place Baltimore Orioles will send a fifth of their 25-man active roster to the 2016 All-Star game in San Diego.

Third baseman Manny Machado was voted in as the starting third baseman, while outfielder Mark Trumbo and catcher Matt Wieters were named as reserves. Baltimore relievers Zach Britton and Brad Brach will also be members of the American League team, which is scheduled to take on the National League all-stars on Tuesday, July 12, at Petco Park.

Entering Tuesday's action, the Orioles (47-35) led the AL East by two games, despite having lost five straight.

Machado, who will turn 24 on Wednesday, is enjoying the best year of his young career, hitting .325 with 18 homers and 50 RBIs.

Trumbo, meanwhile, has delivered in a big way since Baltimore signed him in the offseason as a free agent. The 30 year old leads the AL with 24 homers while hitting .280 with 60 RBIs, which is third in the AL.

Wieters, 30, is hitting .268 with nine homers and 37 RBIs.

Britton and Brach, meanwhile, are part of a strong Orioles bullpen. Britton, 28, is 2-1 with 23 saves and a 0.80 ERA. He has yet to blow a save opportunity. Brach, 30, is 5-1 with a 1.01 ERA with a pair of saves.

Wieters will make his fourth All-Star appearance, while Machado is an All-Star for the third time. Britton and Trumbo will become two-time All-Stars. Brach will make his All-Star debut.

Herrera to represent Phillies: The Philadelphia Phillies will have just one All-Star — Odubel Herrera, a 24-year-old outfielder, who is hitting .303 with 10 homers, 32 RBIs and 48 runs scored. He's a first-time All-Star.

Melancon going for Pirates: The Pittsburgh Pirates will send closer Mark Melancon, 31, to San Diego. Melancon is 0-1 with a 1.35 ERA and 24 saves. He's an All-Star for the third time in four years.

Pittsburgh left fielder Starling Marte is among the NL's Final Vote candidates and could become an All-Star for the first time if he gets enough votes. For the first time since 2010, Andrew McCutchen was not named to the NL All-Star team.

Nats have four All-Stars: Four Washington Nationals have been selected, including Bryce Harper (.258, 17 homers, 48 RBIs), who will be one of the starting outfielders for the NL.

Harper will be joined by pitcher Stephen Strasburg (11-0, 2.71 ERA), second baseman Daniel Murphy (.347, 14 homers, 56 RBIs) and catcher Wilson Ramos (.340, 13 homers, 46 RBIs), matching a franchise record for most All-Star selections with four, set in 2012.

Cubs have five All-Star starters: After topping the major leagues during the first half of the season as they seek their first World Series title in more than a century, the Chicago Cubs dominated the NL All-Star roster.

The Cubs became the first team since the 1976 Cincinnati Reds' Big Red Machine to have five players voted as All-Star starters, and seven Chicago players in all were picked. Chicago's entire infield was voted in — first baseman Anthony Rizzo, second baseman Ben Zobrist, shortstop Addison Russell and third baseman Kris Bryant — along with center fielder Dexter Fowler, who hopes to recover from a hamstring strain that has sidelined him since June 18. The only other team to start four infielders was the 1963 St. Louis Cardinals.

Rizzo led NL players with 3.2 million votes, and Zobrist won the closest race by finishing 88 votes ahead of Murphy. Jake Arrieta and Jon Lester were selected for the National League pitching staff.

The game will feature 11 first-time starters, the most since 2005. In a sign of the sport's generational change, 12 of the 17 elected starters are 26 or younger.

Boston gets six All-Stars: Boston has six All-Stars, including four starters. Designated hitter David Ortiz, who is retiring at the end of the season, became a 10-time All-Star and is joined in the lineup by a trio of first-timers: shortstop Xander Bogaerts and outfielders Jackie Bradley Jr. and Mookie Betts. Knuckleballer Steven Wright and closer Craig Kimbrel also were selected.

Kansas City catcher Salvador Perez and first baseman Eric Hosmer were voted to the AL starting lineup along with Houston second baseman Jose Altuve, Machado and Los Angeles outfielder Mike Trout. Perez led all players with nearly 4.97 million votes.

San Francisco catcher Buster Posey was elected in the NL along with New York Mets outfielder Yoenis Cespedes and Harper.

Arrieta is among five first-time All-Stars on the NL pitching staff, joined by New York's Noah Syndergaard and Jeurys Familia, the Los Angeles Dodgers' Kenley Jansen and Miami's A.J. Ramos. Other NL pitchers include Strasburg, the Giants' Madison Bumgarner, the Marlins' Jose Fernandez and Atlanta's Julio Teheran. Washington's Max Scherzer was bypassed.

Andrew Miller and Dellin Betances were picked for the AL bullpen from the New York Yankees' Run BMC trio but Aroldis Chapman was left off after missing the first 29 games of the season while serving a domestic violence suspension. Carlos Beltran, 39, was also named to the AL side for the Yankees.

Miller and Wright are among seven first-time All-Stars on the AL pitching staff, joined by Tampa Bay's Alex Colome, Toronto's Marco Estrada, Brach, Houston's Marco Estrada and Cleveland's Danny Salazar. Other AL pitchers include Chicago's Chris Sale and Texas' Cole Hamels.

The AL has won the All-Star game three straight times and is 10-3 since the All-Star winner has determined home-field advantage in the World Series.

The Associated Press contributed to this report.