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BOSTON — Kevin Gausman's empty run continues.

The right-hander was tagged for six runs in three innings, extending his 2016 winless string to 11 starts, as the Baltimore Orioles lost 6-4 to the Boston Red Sox on Wednesday night.

Gausman (0-4) gave up seven hits and was knocked out after a five-run third. He's had seven no-decisions this season and is now winless in his last 17 road starts, dating back to August 2014.

Hanley Ramirez hit his first homer in more than a month and knuckleballer Steven Wright was solid into the eighth inning for Boston.

"It's frustrating, I'm kind of in a little funk right now and I feel like I'm throwing the ball well, but a couple of pitches here and there," Gausman said. "I hang a breaking ball when you can't do that — and Hanley Ramirez is a pretty good hitter, so he put a good swing on it."

Adam Jones hit a two-run homer for the Orioles, who ended a stretch of five straight multi-homer games.

The Orioles were shut out through the first six innings before scoring twice in both the seventh and eighth. Boston's fielders made a handful of nice plays.

"They made it seem like four or five real good defensive plays there, or we'd be looking at a different type of game," Baltimore manager Buck Showalter said.

Xander Bogaerts and David Ortiz each had two singles and an RBI for the Red Sox, who rebounded from a 3-2 loss in the series opener on Tuesday for just their fourth win in 11 games.

Wright (8-4) allowed three runs and six hits, struck out four, walked one and hit two batters. He entered with an AL-best ERA that rose from 2.09 to 2.22 by holding an opponent to three or fewer runs for the 12th time in his 13 starts.

Leading 1-0 in the third, the Red Sox batted around and scored five runs against Gausman. Bogaerts and Ortiz opened the scoring with consecutive RBI singles.

Ramirez then hit first-pitch slider over the Green Monster completely out of Fenway Park for his first homer since May 10, ending a homerless drought of 110 at-bats.

Jones homered into the Monster seats with two outs in the seventh.

Wright was lifted after a one-out walk in the eighth. Matt Wieters and Jonathan Schoop had consecutive run-scoring hits off Junichi Tazawa.

Craig Kimbrel got the final three outs for his 15th save.

Travis Shaw's RBI single in the second made it 1-0.

TRAINER'S ROOM

Orioles: Showalter said SS J.J. Hardy (fractured left foot) could be back with the club Friday. He had two singles in three at-bats for Double-A Bowie in his first rehab game on Tuesday. ... Showalter also said RHP Darren O'Day (strained hamstring) may not be ready to come off the DL on Sunday when he's eligible.

Red Sox: RHP Joe Kelly, demoted to Triple-A Pawtucket earlier this month, is still only throwing on flat ground after he sustained a groin injury in a Triple-A start on June 7.

FLASH THAT LEATHER

Boston made four nice plays in the field.

Second baseman Dustin Pedroia made a pair of sliding stops, third baseman Shaw dove to his right for a hard grounder and RF Mookie Betts had a running over-the-shoulder grab.

NICE PEN

Three Orioles' relievers combined for five scoreless innings.

UP NEXT

Orioles: RHP Tyler Wilson (2-5, 4.73 ERA) is in line to start the series finale on Thursday. He's allowed 10 runs on 14 hits in 9 2/3 innings over his last two starts.

Red Sox: LHP Eduardo Rodriguez (1-1, 6.06) is slated to make his fourth start of the season after opening on the DL with a right knee injury.

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