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The number of people around the world who have contracted the coronavirus has surged past 500,000, and the United States tops the list, according to a Johns Hopkins University tally.

That comes as U.S. deaths from the pandemic have now topped 1,100, in another grim milestone for a global outbreak that is taking lives and wreaking havoc on economies and established routines of life. Worldwide, the death toll climbed past 23,000, according to Johns Hopkins’ running count.

In India, where the country’s 1.3 billion people were under orders to stay home, legions of poor were suddenly thrown out of work, and many families were left struggling for something to eat.

“Our first concern is food, not the virus,” said Suresh Kumar, 60, a bicycle rickshaw rider in New Delhi whose family of six relies on his daily earnings of 300 rupees, or $4. “I don’t know how I will manage.”

India has the world’s second-highest number of people living in extreme poverty. Rickshaw drivers, produce peddlers, maids, day laborers and other low-wage workers form the backbone of the economy, and many live day to day on their pay and have no savings to fall back on.

The Indian government announced a 1.7 trillion rupee ($22 billion) economic stimulus package that will deliver monthly rations of grain and lentils to a staggering 800 million people.

More: York-area hospitals not ready for COVID-19 spike, analysis says

Rising death tolls: Around the globe, the death toll rose to about 8,200 in Italy, 4,100 in Spain and 1,700 in France, including a 16-year-old. The U.S. had more than 1,100 deaths, about 400 of them in New York State, the worst hotspot in the nation. Most of those victims were in New York City, where hospitals are getting swamped.

On Thursday, a running count kept by Johns Hopkins University showed the United States now had the most confirmed cases of any country, with more than 82,000. Italy and China, the latter of which was the origin of the outbreak late last year, each had more than 80,000. Collectively the three countries accounted for about half the global total.

Louisiana was quickly becoming another smoldering hotspot. The number of new cases there jumped by more than 500 Thursday, for a total of over 2,300, with 86 deaths, including a 17-year-old, the health department said. The higher infection numbers reflected an increase in testing. New Orleans was gearing up for a possible overflow at hospitals, with plans to treat as many as 3,000 patients at the city’s convention center.

Standstill: From New York’s Fifth Avenue and London’s Piccadilly Circus to the boulevards of Paris and the streets of Rome and Madrid, restaurants, hotels, airlines, giant chains and small shops are all shuttered, and factories across both continents have ground to a halt, as cities, states and entire countries have ordered the closing of nonessential businesses and instructed people to stay home.

Companies in Europe are laying off workers at the fastest pace since 2009, according to surveys of business managers. And the U.S. is bleeding jobs as well: The number of Americans applying for unemployment benefits last week was nearly five times the old record, set in 1982.

Dann Dykas, 37, of Portland, Oregon, was laid off from his job helping design and set up displays for trade shows.

“Everything is so surreal,” he said. “I can’t even get an interview for another job, and we now have to worry more about being careful and taking care of ourselves.”

In a rare positive sign, stocks rallied on Wall Street for the third straight day after an unprecedented $2.2 trillion economic rescue package to help businesses, hospitals and ordinary Americans pull through the crisis won passage in the Senate. The Dow Jones Industrial Average jumped more than 1,350 points, or over 6%.

The rescue plan, which is expected to be voted on in the House on Friday, would dispense checks of $1,200 per adult and $500 per child.

President Donald Trump, meanwhile, announced that federal officials are developing guidelines to rate counties by risk of virus spread, as he aims to ease the restrictions meant to slow the outbreak.

Italy, the eurozone’s third-biggest economy and a major exporter of machinery, textiles and other goods, became perhaps the first Western developed nation to idle most of its industry, extending a shutdown on smaller, nonessential businesses to heavy manufacturers.

Among the companies in Italy that have shut down or rolled back production: Fiat Chrysler, Ferrari, Pirelli tires and Luxottica eyewear, maker of Ray-Bans and Oakleys.

The industrial lobby Confindustria estimates a cost of 70 billion to 100 billion euros ($77 billion-$110 billion) of national wealth a month if 70% of companies are closed, as anticipated.

“We are entering a war economy,” said Confindustria President Vincenzo Boccia.

Elsewhere around the world, South Africa, with the most industrialized economy in Africa, headed into a three-week lockdown starting Friday. The country is already in recession, with an unemployment rate of 29%.

And Britain unveiled another relief effort, this time aimed at the gig economy, many of whose workers are facing financial ruin. The government will give the self-employed grants equal to 80% of their average monthly profits, up to 2,500 pounds ($2,975) per month.

Long reported from Washington, Rising reported from Berlin and Schmall from New Delhi. Associated Press journalists around the world contributed to this report.

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