The protest is planned for Monday at 12:30 p.m. at the Federal Building on Arch street, according to a release from the Earth Quaker Action Team and the Pennsylvania chapter of the Sierra Club. They say the event will include civil disobedience targeting the Obama Administration.
The proposed 1,100-mile pipeline has become a high-profile symbol of the political debate over climate change.
Pipeline supporters, including lawmakers from both parties and many business and labor groups, say the project would create jobs and reduce the need for oil imports. Opponents say the pipeline would carry "dirty oil" that contributes to global warming.
The pipeline would travel from Canada to Nebraska and connect there with existing pipelines.