State police said the Thursday afternoon accident near Loganville on Interstate 83 began after traffic slowed, leading a tractor-trailer driver to rear-end another vehicle and trigger a chain reaction.
The accident involved five cars, four tractor-trailers and a tow truck that was towing two vehicles.
Authorities said none of the injuries is considered life-threatening.
Fuel and hydraulic fluids leaked but were contained by a hazardous materials crew.
The incident closed the northbound lanes for an indefinite period.