WAYNESBURG, Pa.—State police say a collision between a sport utility vehicle and a motorcycle on an interstate in southwestern Pennsylvania has killed four people and sent four others to the hospital.

Police in Greene County say the SUV was heading north on Interstate 79 at about 4:30 p.m. Wednesday when it veered onto the median near the Ruff Creek exit and then collided with a southbound motorcycle and camper.

Police said 47-year-old motorcycle operator Michael Cohen of Oshawa, Ontario and 18-year-old Cullin Frazer and 18-year-old Benjamin Hardy of Waynesburg and 18-year-old Bryon Kerr of Carmichaels in the SUV were all killed.

A 48-year-old woman riding on the motorcycle and three male SUV passengers were taken to Ruby Memorial Hospital in Morgantown, W.Va. with injuries that are not believed to be life-threatening.