Ayelet Frisch said Peres was feeling well and preparing to work from home after his discharge on Sunday. She said he would resume public appearances later in the week.
The president underwent surgery Friday, shortly after returning from a week-long state visit to Canada where the hernia was discovered.
Peres, a Nobel Peace Prize winner and former Israeli premier, is known for his long work days and busy schedule.
In 2007, he was elected to the nonpartisan, ceremonial office of president for a seven-year term.